Get Permission Kakde, Kale, and Sanap: Advances in biomaterials for dental implants: A comprehensive review of progress, challenges, and future trends


Introduction

Dental implants revolutionized restorative dentistry by providing the patient with a permanent end highly effective remedy for the restoration of missing teeth. A dental implant consists of a titanium or A surgically positioned titanium alloy post, consisting of artificial structure with the jawbone is itself a composite. This provides support to a prosthetic tooth. Successful working of dental implants has been contributed to their ability to reinstate function and aesthetic, significantly enhancing the quality of life for patients.1 The procedure involves not only the implant itself but also adjacent treatments". These procedures include soft tissue management or bone grafting, based on the patient's status. Over Dental implants have, in the past decades, effectively showcased themselves as one of the most reliable techniques for Treating edentulism and tooth loss promotes long-term solutions with a high patient satisfaction.2 Biomaterials are, therefore, of paramount importance to the success of dental implants, because they directly affect the incorporation of the implant with the adjacent bone and soft tissues. For an implant to function optimally, must demonstrate such properties as biocompatibility mechanical strength, and resistance to corrosion, all these forming critical qualities to the long lasting stability and effectiveness of the implant. The interaction between the biomaterial and bone tissue, called Osseointegration has been considered as the best indication of the success of dental implantation. Advance Biomaterials are designed to improve osseointegration and minimize the likelihood of complications such as implant failure or peri-implantitis, and ultimately improve patient outcomes.3 This review aims to give an overview of the latest advances in biomaterials used for The paper examines dental implants focusing on the properties and benefits that enable clinical effectiveness. Dental implants. Study of different material types such as metals, ceramics, and this review will concentrate on the challenges of composites in relation to being biocompatible. Osseo integration and lifespan. In addition, the criteria of this review are both current applications and future directions in biomaterial development, offering a Get a full appreciation of how the materials affect implant performance.4 Titanium and its alloys have become the preferred materials for various implants due to their excellent biocompatibility and mechanical properties. While the different bone grafting techniques employed in orthopedic surgery, such as autografting, allografting, and xenografting, showcasing the evolution of bone regeneration strategies.

Historical Perspective

The evolution of material use in dental implants has advanced drastically, where innovations about the biomaterials have played the important role in enhancing implant functionality and the overall outcome achieved in patients.5 The pioneer works on dental implants used a variety of nondurable materials, which attained moderate success. However, during the past decades, scientific development in the areas of material science and clinical dentistry facilitated enhancement of implant materials, ultimately ensuring greater reliability and implant-related success rates.6

Evolution of materials used in dental implants

In the early 20th century, materials used for dental implants were gold, ivory, and several metals; yet these materials proved to be subject to corrosion and failed to integrate into osseous tissue effectively. The idea of using titanium for dental implants came in the 1960s thanks to research by Swedish scientist Per-Ingvar Brånemark. Brånemark discovered that titanium had the ability to osseointegrate, or directly attach to osseous tissue, which he termed "osseointegration." His discovery revolutionized the realm of dental implantology with the introduction of titanium as the benchmark material for implants, attributed by its remarkable biocompatibility, robustness, and resistance against corrosion.7 The introduction of titanium hugely increased the success rates in dental implants and made more precise outcomes in the field of dental restoration. As more became known about titanium and its association with osseous tissue, new materials were discovered that added titanium alloys-for example, Ti-6Al-4V-and were intended to be stronger, reducing the probability of a failed implant.8

Milestones in biomaterial research for implants

The most important developments in the area of biomaterials associated with dental implants concern biological, mechanical, and aesthetic improvements in implantation materials. From the 1980s to the 1990s, surface modification of titanium implants was a main field of innovation. It has been found that the surface topography of titanium implants could be modified using techniques such as sandblasting or acid etching to increase the surface roughness, thus improving adhesion and integration with the bone. These modifications, along with the over-layers like hydroxyapatite (HA), were aimed at replicating the real mineral content of bone, thus allowing the osseointegration process to be faster and more predictable.9 While the science was maturing towards the 2000s, naturally, the trend was shifted towards ceramic materials, including zirconia as a possible alternative to titanium. Although zirconia implants provide some benefits, such as aesthetic outcomes. Zirconia is a white ceramic material, which by itself is biocompatible and provides a much more aesthetically pleasing color compared to the metallic shade of titanium. This is why zirconia becomes highly desirable for use in anterior implants, where aesthetic appeal is of prime importance. Furthermore, zirconia is more resistant to corrosion and plaque accumulation compared to titanium, which further makes it an attractive choice. Although promising clinical outcomes associated with zirconia implants have been reported, their long-term behavior, specifically regarding mechanical properties and osseointegration, continues to be studied actively.4

Properties of Ideal Biomaterials for Dental Implants

The success of dental implants mainly hinges on the materials used in fabricating them. Ideally, any biomaterial used in creating a dental implant should exhibit appropriate properties for long-term performance with biosafety and aesthetic acceptability. The required properties are, therefore, biocompatibility and osseointegration; mechanical strength and durability; and resistance to corrosion and wear as well as aesthetic and cosmetic properties. All this is vital to ensure that there is satisfactory performance of the dental implants in the rather hostile environment of the oral cavity.8

Biocompatibility and osseointegration

Biocompatibility is one of the critical characteristics that any material used in the formation of dental implants must have. In order for an implant to be successful, it has to integrate well with all adjacent tissues, most important of which is the bone. Osseointegration has been defined as direct bone contact established by the implant material in the absence of any fibrous tissue between them first reported by Per-Ingvar Brånemark during the 1960s.5 Titanium and titanium alloys are widely used in dental implants. Considerable improvement in durability is associated with their superior biocompatibility, which promotes osseointegration. Other materials apart from titanium have been studied for biocompatibility, such as zirconia. However, further work is needed to fully understand the osseointegration potential of these other materials.7

The surface properties of the material are also essential in implant osseointegration. The surface modifications, such as acid etching and sandblasting, in addition to bioactive coatings such as hydroxyapatite, have been used to improve the interaction between the implant material and bone. These modifications increase the surface roughness, hence promoting better attachment of bone cells and faster healing.10 In the excellent biocompatibility means titanium and its alloys have the ability to integrate seamlessly with living bone tissue, minimizing the risk of rejection or adverse immune responses.

Mechanical strength and durability

The mechanical properties of a dental implant-that is, strength, hardness, and fatigue resistance-decide its performance over the constant forces applied during a chewing and biting cycle. High loads must be resisted in the absence of fracture and deformation for long periods with implants. Titanium and many of its alloys, which include Ti-6Al-4V, have excellent strength and fatigue resistance and are thus being used in dental implants.11

Another alternative material that is gaining much attention is because of its excellent strength and fracture toughness, especially when used in anterior implants wherein aesthetic considerations are paramount. However, zirconia can be brittle under some conditions and is less resistant to fatigue compared with titanium, which limits its use in some clinical situations. Continuity in developing composite materials as well as exploring different alloys for combining together is extending the range of available materials for implants with an emphasis on obtaining both strength and flexibility to achieve the needs of patients which vary in requirements.12 The material's mechanical performance is clearly explained, highlighting its potential.

Corrosion and wear resistance

Corrosion resistance is another vital characteristic of implant materials, as the oral environment is highly challenging, with the presence of saliva, food acids, and bacterial activity. A successful implant material must resist corrosion to maintain its mechanical properties and prevent degradation over time. Titanium is particularly well-regarded for its resistance to corrosion, largely due to the formation of a stable oxide layer on its surface, which protects it from degradation.13

In addition to corrosion resistance, dental implants must exhibit wear resistance to minimize the abrasion between the implant and opposing teeth. This is particularly important in the case of prosthetic restorations placed on implants. Titanium alloys generally perform well in this respect, though the wear properties of ceramics like zirconia are also noteworthy.14 The visual representation clearly highlights the reduced corrosion rates and wear depths observed in the material, coating, or treatment, underscoring its enhanced durability.

Aesthetic considerations

Aesthetic considerations are increasingly important, especially for patients seeking implants in the anterior regions of the mouth. Titanium implants, while biocompatible and strong, have a metallic appearance that may show through the gums, especially in patients with thin gingival tissue. This aesthetic limitation has driven the development of alternative materials such as zirconia, which offers a more natural, tooth-like color and better aesthetic outcomes in visible areas.15

The aesthetic properties of zirconia are complemented by its ability to encourage healthy growth of soft tissues, reducing the prominence of the margin of the implant and allowing for a better overall esthetic appearance of the restorative prosthesis. However, zirconia is limited by poor mechanical strength and tends to fracture rather than bend when subjected to stress, and therefore it is used primarily only in locations within the mouth where loads are relatively smaller. The mechanical properties of ceramic implants are continually evolving, all while maintaining aesthetic benefits.16

Traditional Biomaterials for Dental Implants

Conventional biomaterials employed in dental implants comprise metals including titanium and its alloys, ceramics like zirconia, and polymers, with each type offering unique benefits to the functionality of the implant as well as to patient contentment. These materials have served as the cornerstone of dental implantology for many years, and their characteristics are perpetually developing alongside technological progress.

Titanium and its alloys

The first application of titanium and its alloys in dental implants occurred when Per-Ingvar Brånemark pioneered the work in the 1960s introducing the concept of osseointegration. Several advantages of titanium make it a popular material for dental implantology.17

Ceramics (e.g., Zirconia)

Ceramic materials, particularly zirconia, have gained popularity as alternatives to titanium in dental implants, especially for patients seeking superior aesthetic outcomes.18

Aesthetic benefits

Zirconia, a white ceramic, is highly valued for its aesthetic benefits. It closely resembles the natural color of teeth, making it ideal for implants in the visible, anterior regions of the mouth. Zirconia also promotes healthy tissue integration, as its color and smooth surface reduce the risk of visible implant margins or gum discoloration, which can be an issue with titanium implants. This makes zirconia particularly appealing for patients who are concerned with the appearance of their implants and wish for a more natural-looking restoration.19

Emerging Biomaterials and Innovations

Dental implant field is constantly evolving, thanks to development and improvements in biomaterial that improve the result of implanting. New generation materials provide improvements in terms of osseointegration, mechanical properties, esthetics, and personalized templating. Such innovations are the enhanced surface modification, bioactive materials, composites, and bonded biomaterial through the use of 3D printing. These developments are designed to override the shortcomings found with traditional materials than offer improved longevity and satisfaction among patients.20

Surface modifications

Surface modification in dentistry has helped to change the performance of dental implants in a great way. By changing the surface properties of implant materials, investigators have decreased the adhesion of bacteria substantially. Enhanced bone to implant contact, faster healing times, and increased overall success rates of implants.21

Nanostructured surfaces

Nanotechnology has delivered nanostructure surfaces on dental implants that can have a stimulating effect on the surrounding bone tissue. Three-dimensional nanostructures including nanopillars, nanofibers and nanopores are fashioned to match the topographical features of ECM to improve cell attachment and growth. These surface changes enhance osteoblast response, enhance bone apposition, and also status of osseointegration.

Additional coatings on implant surface assist in improving the rate and strength of bonding of the implant to the osseous tissues. The most common of the coatings is hydroxyapatite (HA) which is a naturally occurring substance – calcium phosphate – very similar to the mineral content of bone. HA coatings have also been established to increase bone apposition and also to offer a bioactive substrate which supports implant osseointegration. Similar coatings, including titanium plasma-sprayed coatings and bioactive glass coatings, have been also designed for enhancing the bone apparition around the implants. These coatings enhance anchorage of materials or devices to osseous tissues by increasing the rate of bone apposition while the overall biological interaction between the implant and the biological environment is enhanced due to over coating.22

Calcium phosphates (e.g., Hydroxyapatite)

Calcium phosphates, particularly hydroxyapatite (HA), are widely used in dental implants due to their excellent osteoconductive properties. HA is chemically similar to the mineral phase of natural bone, allowing it to integrate seamlessly with surrounding bone tissue. It promotes the formation of new bone cells and supports the repair of bone defects. HA coatings on titanium implants enhance bone-implant contact and provide a more favorable environment for osseointegration. Additionally, calcium phosphate-based materials can release calcium and phosphate ions, which further stimulate bone formation.23

Bioactive glass

Bioactive nother class of bioactive materials that have shown great promise in dental implants. Bioactive glass reacts with the surrounding tissues to form a stable bond, enhancing osteointegration. It stimulates osteoblasts and promotes the deposition of bone-forming minerals at the interface between the implant and bone.24 Bioactive glass can be used as a coating material or incorporated into composite implants to enhance their biocompatibility and bioactivity. Moreover, bioactive glasses can help combat peri-implantitis by promoting a favorable biological response and reducing inflammation around the implant site.25

Composite materials

Composite materh combine different materials to achieve superior mechanical properties, have become a key area of research in dental implantology. These hybrid materials offer a balance between strength, functionality, and aesthetics.26

3D-Printed biomaterials

The presented technique of 3D printe production of dental implants is certainly one of the greatest innovations concerning implant manufacturing, as it enables highly individualized implant construction and ensures a very high degree of accuracy. This technology makes it possible to design implants that correspond in shape to the patient’s anatomy, with a desirable level of accuracy.27

Customization and precision in implant design

The advantages of 3D printing for implants include the capacity to create geometries and precise shapes that were previously unachievable with conventional production methods. Utilizing precise patient-specific imaging for implant planning, dental implant professionals are now employing systems such as CBCCT, CT scans, and MRIs to position implants that accurately reflect the lengths, widths, and locations of the bone anatomy, thereby enhancing implant stability and patient comfort.28

Role of Biomaterials in Soft and Hard Tissue Integration

While dental implants have demonstrated significant success, their efficacy relies on osseointegration with bone tissue as well as integration with soft tissues. The relationship between dental implants and both soft and hard tissues should be analyzed using the proposed idea. Hard tissues are essential for the long-term success, stability, and functionality of implants. Advancements in biomaterial creation have significantly enhanced the augmentation of soft tissue. Mitigating early implant failure caused by bacterial adherence and enhancing bone regeneration for successful implant outcomes. This section examines how biomaterials can improve interactions and implant results.29

Enhancing soft tissue adhesion

The integration of soft tissues with the dental implant is essential for the prosthesis's success. The encompassing softness. Its position necessitates that tissues, such as the gingiva, establish a stable and functional adaption around it.

Surface modifications for soft tissue integration

Titanium, the most widely used material for dental implants, has been found to facilitate soft tissue adhesion. However, surface modifications are being explored to improve soft tissue attachment further. One promising approach is the incorporation of hydrophilic coatings or plasma treatment of the titanium surface. These treatments enhance the surface energy, promoting the adhesion of fibroblasts, which are essential for forming a healthy soft tissue barrier around the implant.30

Bioactive coatings

Research is being conducted on items containing collagen, peptides, and extracellular matrix components derived from natural materials for application as coatings on implants after soft tissue adhesion. Collagen coating enhances fibroblast adhesion and proliferation, hence facilitating tissue repair and physiologically sealing tissue layers. Moreover, synthesized oligopeptides like RGD (Arg-Gly-Asp), which embodies the cell adhesion motif of the extracellular matrix, augment soft tissue attachment to titanium implants.31

Calcium phosphate coatings

Calcium phosphate-based biomaterials encompass hydroxyapatite (HA), which facilitates improved bone filling and healing surrounding dental implants. Hyaluronic acid is biocompatible and bioactive; it serves as an osteoconductive substrate that promotes osteoblast adhesion and development. The utilization of HA or TCP was shown to improve osseointegration by enabling the implant's surface to adhere to bone tissue. These coatings can affect the contact between the implant and bone to facilitate the osteogenesis process and subsequent new bone development surrounding the implant.32

Prevention of peri-implant diseases

Peri-implant diseases are conditions that impact the tissues around implants, encompassing peri-implant mucositis and peri-implantitis; these illnesses frequently lead to implant failure. Peri-implant mucositis manifests as inflammation within the mucosal band around the implant, whereas peri-implantitis is characterized by inflammation affecting both soft and hard structures, accompanied by bone loss. These illnesses are detrimental to the long-term success of implants; therefore, their prevention is crucial, with biomaterials playing a significant role in this regard.33

Antibacterial coatings and surface modifications

One strategy for eradicating peri-implant illnesses involves the application of antibacterial coatings or modification of surface features to regulate bacterial adhesion surrounding the implant. Silver, copper, and zinc are materials that have demonstrated significant antibacterial properties. These materials may be included into the design of the implant surface or applied as a coating to reduce bacterial adhesion and subsequent biofilm development on the implant surface. Furthermore, additional alterations to the surface that increase the roughness of the implant will enhance the adhesion of antimicrobial agents to the implant, thereby diminishing the risk of infection.34

Antibiotic-loaded biomaterials

Antibiotic-embedded biomaterials have been reported to prevent peri-implant infections. Antibiotic delivery has been tailored to the implant site using carriers such hydrogel-based systems or biodegradable polymers to reduce bacterial burden and, consequently, infection. These materials gradually release antibiotics, which is crucial for short-term applications, such as in the first postoperative period or for patients with heightened infection susceptibility. These biomaterials contribute to decreasing the incidence of peri-implant illnesses by mitigating the early start of infection.35

Challenges and Limitations

Despite significant advancements in biomaterials and the success rates of dental implants, numerous difficulties and limitations persist. This encompasses issues related to biodegradable and stable products, expected challenges such as accessibility, as well as costs and complexities. Manufacture and the possible allergic reactions; infections. Addressing these problems is essential for the ongoing advancement of dental implant material technology to achieve optimal long-term clinical outcomes.36

Biodegradability and long-term stability

This is particularly relevant regarding the biodegradability and stability of certain biomaterials, notably in the context of dental implants. Although certain materials, such as bioactive glasses and polymers, are designed to degrade over time, this can occasionally impair the effectiveness of the implant. There is a specific risk of inadequate mechanical support for the implant due to the rapid deterioration of some materials.37

Challenges with biodegradable materials

Polymers and bioactive ceramics for bone regeneration and soft tissue integration represent the most promising materials; yet, their breakdown requires regulation.38 However, if the material resorbs very rapidly, it may fail to provide sufficient support for future bone development and may potentially become unstable. Conversely, if degradation occurs slowly, it may lead to issues related to the persistence of foreign elements in the body, including chronic inflammation and an increased risk of infection. Therefore, the design of the implant and the utilization of advanced biomaterials with regulated degrading properties are essential to maintain the implant's mechanical integrity and functionality over time.39

Titanium and its alloys

Conversely, conventional materials like titanium exhibit excellent long-term stability and mechanical qualities. Nonetheless, titanium, as a passive material, may not facilitate superior osseointegration compared to bioactive materials that promote bone development. The pursuit of materials that offer an optimal balance of biocompatibility and mechanical qualities, while exhibiting durability over time, continues to pose a significant challenge in the research of biomaterials for dental implants.40

Future Directions

The field of biomaterials in dental implants is always evolving, with research and innovations that challenge the science and potential of dental implantology. Prospective Instructions for modifying these materials focus on developing new biomaterials that can markedly improve the clinical efficacy of dental implants while simultaneously addressing the imperative for sustainability. The newly adopted concept encompasses targeted medicines, personalized treatments, and adaptable devices. The rising trends encompass smart technology, which the author attributes to its significant contribution to the aforementioned trends' development.41

Biomaterials, the application of artificial intelligence in biomaterial construction, and the role of artificial intelligence in biomaterial science. The utilization of artificial intelligence in biomaterials, the function of artificial intelligence in biomaterial engineering, the development of sustainable and eco-friendly products, and the innovation of smart and multifunctional implants that outperform conventional alternatives. This section aims to examine the prospective future applications of these procedures and their alleged impacts on dental implantology. 42

Smart biomaterials

Intelligent materials are crucial to dental implant research due to their ability to modify properties in response to external variables, such variations in temperature, pH levels, or the presence of specific ions. These materials can be engineered to administer therapeutic chemicals in a regulated manner to facilitate the body's self-healing processes and prevent setbacks from infections or more inflammation.43

Drug-eluting implants

Currently, the most talked and novel category of smart biomaterials is drug-releasing dental implants. These implants are engineered to deliver medications or antimicrobial agents to the surrounding tissues in a controlled manner, avoiding a rapid release of large doses. The localized distribution of antibiotics or anti-inflammatory agents at the implant surface could significantly reduce peri-implant infections and promote expedited tissue healing due to diminished inflammation. A drug-eluting implant may reduce the likelihood of systemic drug administration, which is associated with hazardous side effects, while potentially enhancing patient compliance due to localized drug release.44

Responsive materials

Other advanced biomaterials in development possess the capability to alter their properties in response to mechanical stress, temperature, or chemical stimuli within the body.33 Consequently, materials that react to mechanical stress or bone remodeling by releasing substances such as growth factors or osteoinductive agents may improve osseointegration and, as a result, implant stability.32 Similarly, pH-sensitive delivery systems are materials that release specific therapeutic compounds in low pH environments, which can aid in addressing infections surrounding existing implants, particularly in the context of bacterial biofilms.45

Role of AI in biomaterial design

Machine learning, particularly artificial intelligence, is presently transforming the development, testing, and enhancement of dental biomaterials for implants. For instance, AI can analyze large datasets, simulate material interactions with biological systems, and forecast a substance's behavior within the human body.46

Material property prediction

Artificial intelligence can predict the mechanical, biological, and chemical properties of new biomaterials prior to their actual production. This will aid investigators in assessing the biocompatibility, strength, and durability of the materials comprising dental implants. Machine learning methods can analyze data from previous studies to identify the optimal alloy combinations for osseointegration and the most effective surface improvements for soft tissue adhesion.47

Biodegradable materials

Greater resources are being allocated to the development of implants rather than titanium since materials made from natural polymers (chitosan, alginate) are labeled as biodegradable. These materials are designed for predictable and safe biodegradation within the bodily environment to reduce environmental impact. Biodegradable materials may also possess the capability to promote bone regeneration at the location, eliminating the need for extraction upon healing, hence rendering subsequent procedures unnecessary.48

Recycling titanium

The reprocessing of titanium and other metals utilized in dental implants. The implant frame is constructed from titanium, a highly robust and biocompatible material; yet, the energy required for metal extraction and processing is substantial. Efforts to enhance the recycling methods for titanium extracted from removed implants or waste are now underway to mitigate environmental impacts associated with production. Alternative solutions for reducing the carbon footprint of dental implants encompass the implementation of sustainable production practices, such as the use of renewable energy sources and the exploration of improved titanium production procedures.49

Multi-functional implants for enhanced performance

Today, the development of multifunctional implants has emerged as a pivotal focus in the research of dental implants. A fixed hybrid prosthesis is designed to serve multiple functions beyond merely offering skeletal support. These implants can integrate several features that will enhance both mechanical and biological performance.50

Multi-functional coatings and composites

A newly emerging subcategory in multi-functional implants involves the fabrication of various layers of bioactive coatings and a minimum of two types of composites for multifunctional applications.51 For instance, implants can be covered with a coating that possesses both antibacterial characteristics and bioactivity that fosters bone formation. These implants would be osseointegrative, reduce the occurrence of peri-implant illnesses, and simultaneously address infection control measures.52

Integration of sensors and monitoring systems

A potential advancement may involve integrating sensors into existing dental implants. These sensors may also reveal the state of adjacent tissues, signal an infection or inflammation, or alert both the patient and the dentist. Such implants could provide assessments of osseointegration and the condition of the soft tissues, allowing for early intervention if necessary. This would represent a significant shift from existing implant dentistry techniques, utilizing devices that adapt to user needs and provide continuous evaluation of implant condition.52 Compared to traditional monitoring methods, sensor-enabled monitoring provides more accurate and timely data, leading to improved crop yields and quality.

Enhanced aesthetic functions

Regarding aesthetics, such multifunctional implants may emulate the appearance and functionality of natural teeth; they could also incorporate additional features, such as illumination at the implantation site to enhance the patient's visibility post-operation or to serve as a reminder for the requisite care of surrounding soft tissues.53 Implants may be constructed using photochromic materials that alter color in reaction to the pH of adjacent tissue, thereby creating a novel approach for evaluating the health of the implant site.54, 55, 56

Conclusion

The progress in the biomaterials used for dental implants has dramatically revolutionized restorative dentistry through marked improvements in clinical outcomes, patient satisfaction, and the long-term success rates of implants. Biomaterials are important to achieve smooth integration of implants with hard and soft tissues, and new developments including bioactive coatings, nanostructured surfaces, and calcium phosphate-based materials address critical problems such as osseointegration and tissue adhesion. Titanium and zirconia have become the established workhorses, and newer technologies of 3D printing, bioactive glass, and hybrid composites all offer higher performance and more customizability. Despite all the progress, there remain issues with biodegradability of materials, cost feasibility, and susceptibility to infections or immune reactions. All these point to a continuous need for research on biomaterials that must have mechanical strength, be biocompatible, and aesthetically pleasing. Future directions include smart, environment-friendly biomaterials, drug-releasing implants, and artificial intelligence capable of personalized implant design and predictive analytics. Such breakthroughs further cement the promise of sustainability, accuracy, and multifunctional performance. In conclusion, continuous development in biomaterials not only enhances the efficiency of dental implants but also opens up new horizons for dental implantology, allowing for the creation of more intelligent, secure, and accessible solutions that transform patient care and outcomes.

Source of Funding

None.

Conflict of Interest

None.

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Received : 04-12-2024

Accepted : 09-12-2024


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https://doi.org/ 10.18231/j.ijmi.2024.034


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